Assessment of subclinical diabetic cardiomyopathy by speckle?tracking imaging

Biomarker and imaging responses to spironolactone in subclinical diabetic cardiomyopathy.

BACKGROUND Subclinical diabetic cardiomyopathy (DCM) is frequent in asymptomatic subjects with type 2 diabetes (T2DM). We sought the response of functional and fibrosis markers to therapy in a trial of aldosterone antagonism for treatment of DCM. METHODS Biochemical, anthropometric, and echocardiographic data were measured in 225 subjects with T2DM. Myocardial function was evaluated with stan...

Molecular Imaging of Subclinical Diabetic Retinopathy

129 Vascular complications of diabetes are the most serious manifestations of the disease, and account for most of its morbidity and mortality. Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes. Symptoms of DR are minimal until structural abnormalities are established. Microaneurysms and pericyte loss are found in earlier stages of DR, while capillary n...

Native T1 mapping by cardiovascular resonance imaging detects subclinical cardiomyopathy in patients with systemic lupus erythematosus

Results Sixteen age-matched subjects from the clinical pool with a low pre-test probability and normal CMR acted as a control group. Both groups had normal volumes and global systolic function (ejection fraction (%): control vs. SLE group: 60±13 vs. 56±12, p=0.57) and similar LV mass index (LVmass index (g/ m2): 43±12 vs. 51±12 g/ m2, p=0.18). SLE patients had significantly reduced longitudinal...

Assessment of left ventricular longitudinal function in cats with subclinical hypertrophic cardiomyopathy using tissue Doppler imaging and speckle tracking echocardiography

Hypertrophic cardiomyopathy (HCM) in cats is characterized by concentric left ventricular (LV) hypertrophy and both diastolic and systolic dysfunction. Although impaired cardiac function detected by tissue Doppler imaging (TDI) in cats with HCM was previously reported, reference ranges of TDI in normal cats and cats with HCM have been reported as widely variable. Two-dimensional speckle trackin...

Diabetic cardiomyopathy